Similasan's unique Active Response Formula medicines promptly stimulate the body's natural ability to soothe and relieve ear pain. The active ingredients in homeopathic medications work safely and effectively with no known side effects and no known drug interactions. Now available in a Children's formula! Children's Earache Relief ear drops are made specifically for children with an additional active ingredient, pulsatilla. Pulsatilla is indicated to relieve ear pain that's worse at night. Similasan ear pain products can be used alone or in combination with prescription antibiotics. Similasan Healthy Relief products have provided safe, effective relief to millions of people for over 25 years.